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Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. ==Background== Histones are proteins that package DNA into nucleosomes.〔Youngson, Robert M. (2006).Collins Dictionary of Human Biology. Glasgow: HarperCollins. ISBN 0-00-722134-7.〕 Histones are responsible for maintaining the shape and structure of a nucleosome. One chromatin molecule is composed of at least one of each core histones per 100 base pairs of DNA.〔 Khorasanizadeh, Sepideh. 2004. The Nucleosome: From Genomic Organization to Genomic Regulation. Department of Biochemistry and Molecular Genetics, University of Virginia Health System. Cellular Biology. Volume 116, Issue 2, , Pages 259–272.〕 There are five families of histones known to date; these histones are termed H1/H5, H2A, H2B, H3, and H4.〔Cox, Michael; Nelson, David R.; Lehninger, Albert L (2005). Lehninger Principles of Biochemistry. San Francisco: W.H. Freeman. ISBN 0-7167-4339-6.〕 H2A is considered a core histone, along with H2B, H3 and H4. Core formation first occurs through the interaction of two H2A molecules.〔Cox, Michael〕 Then, H2A forms a dimer with H2B; the core molecule is complete when H3-H4 also attaches to form a tetramer. Other histone proteins: H1 H2B H3 H4 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Histone H2A」の詳細全文を読む スポンサード リンク
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